Managing women‐specific bleeding in inherited bleeding disorders: A multidisciplinary approach

Controversies in Inherited Bleeding Disorders.

Recent years are witnessing key developments in treatment approaches for congenital bleeding disorders (CBD), in particular the hemophilias, but also other factor deficiencies.1,2 Moreover, cooperative multinational efforts are providing advances in our knowledge of pathophysiological, clinical, and management aspects of these disorders, including the more rare abnormalities.3–6 However, despit...

Management of Inherited Bleeding Disorders in Pregnancy

Evaluation the dentists’ awareness of inherited bleeding disorders and anticoagulants in Shiraz

Background Some of the dental procedures can cause bleeding. Bleeding control can be difficult in some patients because of systemic disease or chronic anticoagulant therapy, so they may be at increased risk for bleeding occurrences or even death following invasive dental procedures. This study was schemed to measure the knowledge of general dentists in Shiraz city regarding coagulation tests ...

Introduction to a series of reviews on inherited bleeding disorders.

Hematology can proudly claim to have led many of the recent advances in the application of molecular science to enhancing the diagnostic and treatment potential for disease. Although every issue of Blood contains new insights into the integration of molecular knowledge for improved clinical care, the paradigm of molecular medicine can be traced to the late 1970s/early 1980s, with advances in un...

Recombinant activated factor VII for bleeding in patients without inherited bleeding disorders.

(1) Recombinant activated factor VII (rFVIIa) is licensed in Canada for the prevention and treatment of bleeding in hemophiliacs, but it is increasingly used to control bleeding in non-hemophilic patients during surgery, or during treatment for severe trauma or intracerebral hemorrhage (ICH). (2) In one clinical trial, there was a significant reduction in mortality among patients with ICH treat...